base transversion 예문

• In e coli , dna polymerases are key enzymes involved in two distinguished pathways contributing to untargeted mutagenesis . replication of dna by pol v ( umuc ) , in the presence of umud1 , reca and single strand binding protein ( ssb ) , is highly mutagenic and exhibits a predominant mutation pattern of base transversion . another error prone polymerase involved in untargeted mutagenesis is pol iv , encoded by dinb gene